Rutin is a plant-based compound found in a variety of fruits and vegetables, including buckwheat, apples, and oranges.
It has been studied for its potential health benefits, including its ability to help regulate blood sugar levels.
Research has shown that rutin may be effective in reducing blood sugar levels in people with diabetes. This is due to its ability to affect several different mechanisms in the body.
One proposed mechanism for the antihyperglycemic effect of rutin is a decrease of carbohydrates absorption from the small intestine. This is thought to be due to rutin’s ability to inhibit the enzymes responsible for breaking down carbohydrates into simple sugars. This reduces the amount of sugar that is absorbed into the bloodstream, which helps to keep blood sugar levels stable.
In addition, rutin has been shown to inhibit tissue gluconeogenesis, which is the process by which the body produces glucose from non-carbohydrate sources. By inhibiting this process, rutin helps to reduce the amount of glucose produced in the body, which helps to keep blood sugar levels stable.
Rutin also has the ability to increase tissue glucose uptake. This means that it helps the body to absorb glucose from the bloodstream more efficiently, which helps to keep blood sugar levels stable.
Finally, rutin has been shown to stimulate insulin secretion from beta cells. This helps to reduce the amount of glucose in the bloodstream, which helps to keep blood sugar levels stable.
In addition to these mechanisms, rutin has also been shown to protect Langerhans islet cells from degeneration. This is important because these cells are responsible for producing insulin, which helps to regulate blood sugar levels.
Overall, research has shown that rutin may be effective in reducing blood sugar levels in people with diabetes. This is due to its ability to affect several different mechanisms in the body, including a decrease of carbohydrates absorption from the small intestine, inhibition of tissue gluconeogenesis, an increase of tissue glucose uptake, stimulation of insulin secretion from beta cells, and protecting Langerhans islet against degeneration. Therefore, rutin may be a useful supplement for people with diabetes who are looking to manage their blood sugar levels.