Hesperidin, a flavonoid found in citrus fruits, has been studied for its potential anti-cancer properties.
Research has shown that hesperidin can generate reactive oxygen species (ROS) in cancer cells and activate mitochondrial pathways (by upregulating caspases) and inhibit kinases, which can induce apoptosis. Apoptosis is a process of programmed cell death, which is important for the body to regulate the growth of cells.
In addition, hesperidin has been found to regulate cell cycle-related proteins, which can arrest cancer cell cycle in G0/G1 phase and G2/M phase. This means that hesperidin can prevent cancer cells from dividing and multiplying, thus helping to stop the spread of cancer.
Studies have also shown that hesperidin can inhibit the growth of several types of cancer cells, including those of breast, prostate, and colorectal cancer. It has also been found to reduce the size of tumors in mice with breast cancer.
Overall, hesperidin appears to have promising anti-cancer properties. However, more research is needed to fully understand its effects and determine its potential as a cancer treatment. It is important to note that hesperidin should not be used as a substitute for traditional cancer treatments, such as chemotherapy and radiation.
In conclusion, hesperidin appears to have potential anti-cancer properties, but more research is needed to fully understand its effects and determine its potential as a cancer treatment.